Map3k11 (NM_022012) Mouse Untagged Clone

CAT#: MC203089

Map3k11 (untagged) - Mouse mitogen-activated protein kinase kinase kinase 11 (Map3k11), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Map3k11
• Synonyms: 2610017K16Rik; Mlk3; PTK1; SPRK
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC047152
  GAAGAAGGGACCGGGGTCGGAGCTGTCGGGGCCCAAGGCACTAGCCCAAGAAGAGGTAGCTTCGGCTCAA CTGGGGACTTTCTCTTACCTCTTGTGCCTGGAGACAACAACCAGAGTCCGGGCGCTGACCCTGGCAGGCC CCACCTTACGGTAGGCGGGCGCTGAAGCCAGGTTCCCAGGACTACTTCGGAACTGAGGGACTCTACTGCT CCAATTCAGCCATGGTGAGGCGCCGGAGGCCAGTGGGCCCCACCCCTCCAGCCTGACCACACTGCCCTTG GTGCCCTCCTCCAAAAGCCCGAGATGCGGGGGGCCGGGAGGCGACACTCCTGGCTCCCCAGAGAGGCGTG GGTCTGGGGCTGAGGGCCAGGGCCCGGATGCCCAGGTTCCGGCTCTAGGGCCTCACAAGCCAGCGGGGGT GGATACCACGGGCACCCGAAGAAGGTCCCCCACACATTCCAACGCCGGCTCCCTGCCATGGAGCCCTTGA AGAACCTCTTCCTCAAGAGCCCGCTGGGGTCATGGAACGGCAGTGGCAGTGGGGGCGGCGGGGGTACCGG TGGAGTCCGGCCGGAGGGGTCTCCGAAGGCAACAGCAGCTTATGCCAATCCTGTCTGGACAGCCCTGTTC GACTATGAGCCCAATGGGCAGGACGAACTAGCCCTGAGGAAGGGCGACCGTGTGGAGGTGCTGTCCAGGG ATGCAGCCATCTCAGGAGATGAGGGCTGGTGGGCGGGCCAGGTGGGTGGCCAGGTGGGCATTTTTCCATC CAACTATGTATCTCGGGGTGGAGGCCCACCCCCCTGTGAGGTGGCCAGCTTCCAGGAGCTGCGACTGGAG GAGGTGATCGGCATCGGTGGCTTCGGCAAGGTCTACCGTGGCAGCTGGCGAGGGGAGCTGGTGGCTGTGA AGGCAGCCCGACAGGACCCTGATGAGGACATCAGTGTAACAGCTGAGAGTGTTCGACAGGAGGCCCGGCT TTTTGCCATGCTGGCCCATCCCAACATCATTGCCCTCAAAGCTGTGTGCCTGGAGGAGCCAAACCTATGC CTGGTGATGGAGTATGCAGCTGGTGGGCCTCTTAGCCGGGCCCTGGCTGGTCGGCGTGTGCCCCCCCATG TGCTGGTCAACTGGGCTGTGCAGATTGCCCGAGGAATGCACTACCTGCACTGTGAGGCTCTGGTGCCTGT GATACACCGAGACCTGAAGTCCAACAACATTCTGTTGCTGCAGCCCATCGAGGGTGACGACATGGAACAC AAGACCCTAAAGATTACTGACTTCGGCCTCGCCCGAGAGTGGCACAAAACCACCCAGATGAGTGCTGCGG GCACCTACGCTTGGATGGCTCCCGAGGTTATCAAGGCCTCCACCTTCTCCAAGGGCAGCGATGTCTGGAG CTTTGGAGTGCTGCTGTGGGAACTGCTGACTGGGGAGGTGCCCTACCGTGGCATCGACTGTCTTGCCGTA GCCTATGGTGTGGCTGTAAACAAGTTAACGTTACCCATCCCATCTACCTGCCCTGAGCCCTTTGCACAAC TCATGGCTGACTGCTGGGCACAGGACCCCCACCGCAGGCCCGACTTCGCCTCCATCCTGCAGCAGTTGGA AGCTCTAGAAGCGCAGGTGCTGCGGGAGATGCCACGGGACTCCTTCCATTCCATGCAGGAAGGCTGGAAA CGCGAGATCCAGGGCCTGTTTGATGAGCTGCGGGCCAAGGAAAAGGAACTACTGAGCCGGGAGGAGGAAC TGACGCGCGCTGCACGTGAGCAGCGGTCCCAGGCGGAGCAGCTGCGACGGCGCGAGCACCTGCTGGCGCA GTGGGAGCTGGAGGTGTTCGAGCGCGAGCTGACGCTGCTACTGCAGCAGGTGGACCGAGAACGGCCGCAC GTGCGCCGCCGCCGGGGCACCTTCAAGCGGAGCAAACTCCGAGCAAGGGACGGCGGAGAACGCATCAGCA TGCCCCTGGATTTCAAACACCGCATCACAGTGCAAGCCTCTCCTGGCCTGGATCGGAGGAGAAACGTGTT CGAGGTTGGGGCTGGGGACTCGCCCACCTTCCCTAGATTCCGAGCCATCCAGTTGGAACCTACAGAATCA GGCCAGACTTGGGGTCGCCAGTCCCCCAGACGTCTTGAAGATTCAAGCAATGGAGAGAGGCGTGCTTGCT GGGCCTGGGGTCCCAGCTCCCCCAAGCCTGGGGAGGCCCAGAACGGGAGGAGACGGTCCCGCATGGATGA AGCCACGTGGTACCTAGATTCAGACGACTCGTCCCCATTAGGGTCCCCTAGTACTCCCCCGGCACTCAAC GGTAATCCTCCAAGGCCTAGCCCCGAGCCAGAGGAGCCACGGAGGGCCGGGCCCACGGAGCGAGGCAATA GCTCTGGGACGCCTAAACTGATCCAACGTGCATTGCTACGGGGGACCGCTCTGCTGGCTTCCCTAGGCCT TGGCCGAGATCTGCAACCTCCAGGAGGCCTGAGCCGTGAACGCGGGGAGTCCCCGACAGCACCACCCCCT GCACAGATGCCCTCACCCTGCCCACCTGAGCTGCCCTCCACCCCGCTCATCCGCCTCTCACAAACAACAC CTGATGCCCATAGTTCACCCACTCCTGGACCCTTATTGCTAGACCTAGGTGTTCCCTCTGGCCAGCCATC AGCCAAGAGCCCTCGACGGGAAGAGACACGTGGGAGAACCGTCTCACCCCCACCAGGAATATCACGCTCT GCTCCTGGCACACCTGGAACCCCTCGCTCACCACCGTTGGGCCTAATCAGCCGACCTCGGCCCTCACCAC TCCGTAGCCGTATTGACCCATGGAGCTTCGTGTCAGCTGGGCCACGGCCTTCACCCCTGCCCTCTCCACA GCCTGCACCCCGACGGGCACCGTGGACCTTATTCCCAGACTCAGATCCCTTCTGGGACTCCCCACCTGCC AACCCCTTCCGGGGAGGCTCCCAGGACTGCAGGACGCAGACCAAAGACATGGGTGCCCAGGCCCCATGGG CACCAGAAGCAGGGCCCTGAGTGGGCCAGACCACACCCCACGCTTCGGCTGCCTTCGAGGAGGCATAGCA TACACTGGAAGAGGAACCAGGAGGCCTCTGTGGCTGCCTTGGTTTCCCCCAGGGACTCTGACCCTTTGGG GGTCAGGAACACTACACTGCACAGAAAGCCTTCACACTGGATGGGGGCTACACCCCACATGCCTACAAAC TGTAGGGACCCCTGACTTACCTGCCCCACTGGGGCCTGACACTGTACCTAGCTGGTTAGGAGGACCAGAG CCTGTCTCAGGGAATTGCCCCCAGGAGCGGTGCAGGGAGCAGGGAGGTCCAGGGGAAAGGGGCTGACCTC AGGTGTCACCAGCACTTTTGACCAAGTCCTGTTACTGTGGCCCCTGTCTCCAAGGCTGAGTTCCTGGACC CCCAACCCTGGAAGTTATTGGAGCCGGGGCTCTCTGGGTGCCTTTCTACTGCCCCGCCAAGGTTGGAGCC TTGGCCTGGGGAGCCAATGAAGCCAAATAAACTTGTAAGCTGTCTCCCCAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_022012
• Insert Size: 2553 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC047152, AAH47152
• RefSeq Size: 3600 bp
• RefSeq ORF: 2553 bp
• Locus ID: 26403
• UniProt ID: Q80XI6
• Cytogenetics: 19 4.34 cM
• Gene Summary: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle (By similarity).[UniProtKB/Swiss-Prot Function]