Pfn2 (NM_019410) Mouse Untagged Clone

CAT#: MC201857

Pfn2 (untagged) - Mouse profilin 2 (Pfn2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Pfn2
• Synonyms: Pfn
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC024363 sequence for NM_019410
  GCCGCTGCTGCGCCTCTGCTCCTGCCGTCCCCGCTGCAGTGCGAAGGGCTCGAAGATGGCCGGTTGGCAG AGCTACGTGGATAACCTGATGTGCGATGGCTGCTGCCAGGAGGCCGCCATTGTCGGCTACTGCGACGCCA AATACGTCTGGGCAGCCACGGCCGGGGGCGTCTTCCAGAGCATCACGCCAGTAGAAATAGATATGATTGT AGGAAAAGACCGGGAAGGTTTCTTTACCAACGGTTTGACTCTTGGAGCAAAGAAGTGTTCTGTGATCAGA GATAGCCTATACGTTGATGGTGACTGCACAATGGACATCCGGACAAAGAGTCAAGGTGGGGAGCCAACAT ACAACGTTGCTGTTGGCAGGGCCGGGAGAGTCTTGGTCTTTGTAATGGGAAAAGAAGGGGTCCATGGAGG CGGATTGAATAAGAAGGCATACTCAATGGCAAAATACTTGAGAGACTCTGGGTTCTAGCTGCTAGGCAGA CTGTTAAGTATTAGGGGAAAATTGCTCTTAAATTTTCCTAGCTGTAAGCTTAAGTCTCCTTTGTATCCCT CTGTTGGTGGGGAAAGGTGTCTTTCTTTCTGCCCCTTCCCCTTAAATAATTGTGTTCATTTTTGTTTTGT TTCCTTGTGTACTCCAGCATTGGTTATAGTCATGGGAAAGGAAGGTGTCCACGCAGGCACAATTAACAAG AAAACATATGAACTCGCTTTATACCTGAAGAGGTCTGTAACCAACCTTTATCTGGCATCATAATTGCAGC ACAATAATGATTTGCATGATATCTTGAAACTGGGGAAGGGGGCATGCCAAGTTGGGCATCACTTCGTCTT AGCAGTTAGTGGATTACTGATTACTAAAATAGGTTAATAGTAAGCAAGGTGCCGGTGTACAGTCTCTAAC TCGATCAGTGTCTTTTCAGCACTTTGGAGCATTTCCTTGGCTCATCTAGTCTTCCTTTTGTAGCGCATGG TTGGGAGGAAAAAGTGCATGCCTCTGTACGTCACACCTTTCTCACCCCTCCCTACCAACACGAGGTGTTT GGTCTGCTTCCATTCTCTTCTGTGTAGTGCCTGGTTTATTTAACTAATTAATACCTCCTCTGTTGATGAG CTATTGAGAGTTGCAGTGTTTTACTTTTTAATACAGTGACTGCACTTGGGACAGACTATTTGTATGTCTA TAGGACATGAAGCGTGCAGCTTGGAGAGCAAAGGCACTTCCTCCCACGACCTTACTGCAGTAACCATACC GATCAAATTCCCAGGGACATTCTGTCATTGCAGTAGCTCAGACCTGTCTTTTCTTGCACACCAGCTGTGC TCTTGAGAAAATGTAAAGGCTGCCATTATGGATATTAGGTATCCCAACATAACCATCTGGAGTGTGTCCA GTTTATTTTTCATAGGACCAATTTTTATTTGCAGCTTAGGTTTTTATATGAAGTTGCATTATTGTGGACT TGGCTGTCTTGTGATGTATTTTTTTCATATGTATCCTGTGCCATACTATTGTTAAAATGAACTGTTGCTA TTGTGAGATGGATTTCCTTTCGAATGGCACTACCTTAGGGACATTCTAGTATTGCTTCTATTGTTTGGGC ATTGTGGATAATGTACAGATTTAAAAACAAATCTTGTTGCTGATTTGTCCATTTCTTTCCCTGCACTTTG TTACATCTGGGATACAGTCTAACTCATCTGACTTAATATGCATTTAAAAAAATGCCATAACTATTAAACA CCTTGTTTACAGACAGATGAAATAAATTTATTCCAACCAAATACTCCAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_019410
• Insert Size: 423 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC024363, AAH24363
• RefSeq Size: 1844 bp
• RefSeq ORF: 423 bp
• Locus ID: 18645
• UniProt ID: Q9JJV2
• Cytogenetics: 3 28.15 cM
• Gene Summary: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.[UniProtKB/Swiss-Prot Function]