Umod (NM_009470) Mouse Untagged Clone

CAT#: MC200811

Umod (untagged) - Mouse uromodulin (Umod), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Umod
• Synonyms: THP; ureh; Urehd; Urehd1; urehr4; uromu
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC012973 sequence for NM_009470
  CCACGCGTCCGCCAGGACAGAGGGCAGAGTGTAAAGGATGGGGATCCCTTTGACCTGGATGCTGCTGGTA ATGATGGTAACCTCCTGGTTCACTCTGGCTGAAGCCAGTAACTCAACAGAAGCGAGACGGTGTTCTGAAT GCCACAACAACGCCACCTGCACGGTGGATGGTGTGGTCACAACGTGCTCCTGCCAGACCGGCTTCACTGG TGATGGGCTGGTGTGTGAGGACATGGATGAGTGTGCTACCCCATGGACTCACAACTGCTCCAACAGCAGC TGTGTGAACACCCCGGGCTCGTTTAAGTGCTCCTGTCAGGATGGTTTTCGTCTGACGCCTGAGCTGAGCT GCACTGATGTGGATGAGTGCTCAGAGCAGGGGCTCAGTAACTGTCATGCCCTGGCCACCTGTGTCAACAC AGAAGGCGACTACTTGTGCGTGTGTCCCGAGGGCTTTACAGGGGATGGTTGGTACTGTGAGTGCTCCCCA GGCTCCTGTGAGCCAGGACTGGACTGCTTGCCCCAGGGCCCGGATGGAAAGCTGGTGTGTCAAGACCCCT GCAATACATATGAGACCCTGACTGAGTACTGGCGCAGCACAGAGTATGGTGTGGGCTACTCCTGTGACGC GGGTCTGCACGGCTGGTACCGGTTCACAGGCCAGGGTGGCGTTCGCATGGCTGAGACCTGTGTGCCCGTC CTGCGATGCAACACGGCGGCACCCATGTGGCTCAATGGCTCTCATCCCTCGAGTAGTGAAGGCATTGTGA GCCGCACGGCCTGTGCACACTGGAGCGACCAATGCTGCCGGTGGTCCACAGAGATCCAGGTGAAGGCTTG CCCAGGTGGCTTCTATATTTACAACTTGACAGCGCCCCCTGAGTGCAATCTGGCTTACTGCACCGATCCT AGTTCCGTGGAGGGGACTTGCGAAGAATGCAGGGTAGATGAAGATTGCATATCGGATAACGGCAGATGGC GCTGCCAGTGTAAACAGGACTCCAACATCACAGATGTCTCCCAATTGGAGTACAGGCTGGAGTGTGGGGC CAATGACATCAAGATGTCCCTCAGAAAGTGCCAGCTACAGAGTTTGGGCTTTATGAATGTCTTCATGTAC CTGAATGACAGACAATGCTCAGGCTTCAGTGAGAGTGATGAACGAGACTGGATGTCCATAGTGACCCCTG CCAGGAATGGTCCCTGTGGGACAGTATTGAGGAGAAACGAAACCCATGCCACCTACAGCAACACCCTCTA CCTGGCAAATGCGATCATCATTCGGGACATCATCATAAGAATGAACTTTGAATGCTCTTACCCTCTGGAC ATGAAAGTCAGCCTGAAGACCTCCCTACAGCCCATGGTCAGTGCCCTGAACATCAGCTTGGGTGGGACAG GCAAGTTCACCGTGCGGATGGCATTGTTCCAGAGCCCTACCTACACACAGCCCCACCAAGGTCCTTCTGT GATGCTGTCCACTGAGGCTTTTCTGTATGTGGGCACCATGCTGGATGGGGGTGACTTGTCCCGGTTTGTA CTGCTAATGACCAACTGCTATGCCACACCCAGTAGCAACTCCACAGACCCTGTGAAATACTTCATTATCC AGGACAGTTGTCCACGTACAGAAGATACAACCATTCAGGTGACAGAGAATGGCGAGTCATCTCAGGCCCG ATTTTCTGTTCAGATGTTCCGGTTTGCAGGAAACTACGACCTTGTCTACCTTCACTGCGAGGTGTACCTA TGTGACTCTACGAGTGAACAGTGTAAACCTACCTGCTCTGGTACTAGATTTCGAAGTGGGAACTTCATAG ATCAGACCCGTGTCCTGAACTTGGGTCCCATAACACGACAAGGTGTCCAGGCCTCAGTGTCCAAGGCTGC TTCCAGCAACTTGAGGCTCCTGAGCATCTGGCTGCTGTTGTTTCCCTCAGCCACTTTGATCTTCATGGTT CAATGATGGAAAGCAGAAAACCTGGTGTGGCTCCCAGCTCACTTCCTGCTGGCCAGGAGTGGGGATGCAG GCTGGTTATCAGCCAGGAGAGAGGGAGCTCACACTGCCTCCAGCTTGCACGTACTCTTTCTTTAATCCTC ACCATCAAAAACAAGTTGGCATCTTTCAGTGCTGTTCTTCCTTCAAATGTGATATGTATGAAGCCCCTGT CTCCTGAAGGAATGTGGCAAAATAATAAGTTTAAAGTATCAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_009470
• Insert Size: 1929 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC012973, AAH12973
• RefSeq Size: 2229 bp
• RefSeq ORF: 1929 bp
• Locus ID: 22242
• UniProt ID: Q91X17
• Cytogenetics: 7 63.88 cM
• Gene Summary: This gene encodes a glycoprotein that is the most abundant protein in mammalian urine under physiological conditions. It is synthesized in the kidney as a glycosyl-phosphatidylinositol anchored protein and released into urine as a soluble form by proteolytic cleavage. It is thought to regulate water and salt balance in the thick ascending limb of Henle and to protect against urinary tract infection and calcium oxalate crystal formation. In mouse deficiency of this gene is associated with increased susceptibility to bacterial infections and formation of calcium crystals in kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.