Ophn1 (NM_052976) Mouse Untagged Clone

CAT#: MC200448

Ophn1 (untagged) - Mouse oligophrenin 1 (Ophn1), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ophn1
• Synonyms: C130037N19Rik; Wtgr
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004845 sequence for NM_052976
  AGCCCTGAAGACCCGAGGAAGACATCCAAAGGGATCCTGTGCTCTCGTTCGGTCTTGGGGTTAGGGCTCG GCCAGCGTGAAAAGGCTGCACCCTGCCGGCGTCAGAAGACGTTGGTAAGCACTCCTGGTCACCCGCAGCC ACCACCGGACTACGCGCTCCAGCTACACACCAGCGGGCGCTCCCAAGAGTTTCATTGGAACAGCCCCTCC GCTATCCTAATCATGGGGCATCCCCCGCTGGAGTTCAGCGACTGCTACCTCGACAGCCCCGATTTCCGCC AGAGGCTCAAGTATTATGAAGAGGAGCTGGAGAGGACCAATAAATTCATCAAAGACGTGATCAAAGACGG CAGCGCGCTTATCAGCGCTATGAGAAATTACTCTTCTGCGGTTCAGAAATTTTCTCAGACACTCCAGTCA TTTCAATTTGATTTCATTGGAGACACGCTGACCGATGATGAGATTAATATAGCGGAATCATTCAAGGAAT TTGCTGAATTGCTCAATGAAGTAGAAAATGAAAGGATGATGATGGTACAAAATGCTAGTGACTTGCTGAT CAAACCCCTGGAAACTTTTCGGAAGGAACAAATAGGTTTTACAAAGGAAAGGAAGAAGAAATTTGAAAAG GATGGTGAGAGGTTTTACTCGCTACTGGACCGCCACTTACATCTGTCATCCAAAAAGAAAGAATCTCAGC TACTAGAGGCAGACCTCCAAGTGGATAAGGAAAGGCACAATTTCTTTGAATCATCTCTTGACTATGTTTA TCAAATTCAGGAAGTCCAGGAGTCAAAGAAGTTCAATATTGTGGAGCCGGTCTTGGCCTTCCTTCATAGC CTCTTCATTTCTAACAGCTTGACTGTGGAGCTCACACAGGATTTCCTGCCATACAAACAACAGCTGCAGC TCAGCTTACAGAATACAAGAAATCATTTCTCCAGTACCCGGGAGGAGATGGAAGAACTTAAGAAAAGGAT GAAAGAAGCCCCTCAGACATGCAAACTTCCAGGACAGCCAACCATTGAAGGCTATCTCTACACACAGGAG AAATGGGCCCTGGGGATATCCTGGGCGAAATACTATTGTCGGTATGAGAAAGAGACCAGGATGCTCACAA TGATACCAATGGAACAGAAGCCAGGTGCTAAGCAGGGACCGGTGGACTTAACTTTGAAGTACTGCGTGAG AAGGAAGACAGAGTCAATTGACAAGAGATTCTGTTTTGATATAGAAACTAATGAAAGACCTGGAACCATC ACTCTGCAGGCGCCTTCCGAAGCCAATAGAAGGCTATGGATGGAAGCCATGGATGGCAAAGAACCTATCT ACCACACTCCTATAACAAAACAGGAAGAAATGGAGCTGAATGAAGTGGGGTTCAAATTTGTTAGGAAGTG CATCAATTTTATTGAGACCAAAGGGATCAAGACAGAAGGGCTGTACCGCACCGTGGGCAGCAACATCCAG GTTCAGAAGCTGCTCTATGCCTTTTTTGATCCAAAATGTCCAGGGGATGTTGATTTCCATAACAGTGACT GGGACATTAAGACAATCACAAGCTCTTTAAAATTCTACCTCAGGAATCTCTCAGAACCTGTCATGACTTA TAAGCTCCATAAAGAACTCGTCTCTGCTGCCAAATCTGACAACCTGGATTACCGTCTGGGGGCTATTCAC TCCCTAGTATATAAGCTACCAGAAAAGAACCGGGAGATGCTGGAACTTCTAATCAAACACTTGGTAAATG TGTGTGAGCACAGCAAAGAGAATCTTATGACACCTTCCAATATGGGGGTGATCTTTGGGCCCACCCTGAT GAGAGCTCAAGAGGACACTGTGGCTGCTATGATGAACATCAAATTCCAGAACATTGTGGTAGAAATCCTG ATTGAACACTTTGGCAAGATTTATTTAGGTCCACCCGAAGATAGCCAAGTACCTCCAGTGCCTCCACCTC GAGTGACAGCAAGAAGACACAAACCAATCACAATCTCAAAGCGCTTGCTGAGAGAAAAGACTGTGTTCTA TACTTCTTCCCTGGATGAAAATAAAGATGAAAGTCACCATCAAACTCCTAATGGTACAATCACTAGCAAC CTGGATCCCCCCAAGCTACTGCAGCACCTCAAACCACCCATGCAAAAAAGTGGGGAAACTGACCCTGGAA GAAAGTCCCCAAGCAGACCTGTTTCTGACTGTCAATCGGAGCCCTGCCTAGAGACGGATGTGGGGAGGTT GTTATTTAGGTTGCAGGATGGAGGGACCAAGGCTACTCCAAAGGCTTCCAATGGACCTGTTCCAGGCTCT GGACACACAAAGACCTCCTCTTTCCATATAAGGAGACCAGCTCCCAGGCCAATGGCTCACCACAAGGAAG GCGATACTGACGGTTTCAGCAAAGTCCGGCCCCCAGGAGAAAAGCAAACAATCATCCGTCCTCCGGTGAG GCCCCCAGACCCTCCTTGCCGGTCCATCACTCCACAAAAGCCAGAGCCAAAGCCAGAAACAGGGTCTGGC AATGCAGACGAAATCCCATCATCCGTGGTGGCATCTAGGACCAGATTCTTTGAAACAGCTTCCCGGAAAA CTGGAAGTTCTCAAGGAAAACTTCCTGGAGATGAGAGTTGAGGCCACAGGTTTGAAAGGACTTGGCCTTG AGGGACCCTTTTTTGGATGGGAAAGGGTCTACTTCAAACCCTTGTGAGCTATTGGTGCTGAAGAGCAGCT CTTTCTGGCCTTGTAGGGTTCAGTGTCTGGGAACCTATAAAATAAGGAACACATGTCTTAGGCAAAAAAA AAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_052976
• Insert Size: 2409 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC004845, AAH04845
• RefSeq Size: 2809 bp
• RefSeq ORF: 2409 bp
• Locus ID: 94190
• UniProt ID: Q99J31
• Cytogenetics: X C3
• Gene Summary: Stimulates GTP hydrolysis of members of the Rho family. Its action on RHOA activity and signaling is implicated in growth and stabilization of dendritic spines, and therefore in synaptic function. Critical for the stabilization of AMPA receptors at postsynaptic sites. Critical for the regulation of synaptic vesicle endocytosis at presynaptic terminals (By similarity). Required for the localization of NR1D1 to dendrites, can suppress its repressor activity and protect it from proteasomal degradation.[UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.