Grb7 (NM_010346) Mouse Untagged Clone

CAT#: MC200123

Grb7 (untagged) - Mouse growth factor receptor bound protein 7 (Grb7), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Grb7
• Synonyms: mKIAA4028
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC003295 sequence for NM_010346
  CTATATTCTCCCGCCTCAACATTCCAAAGGCGGGATAGCCTTTCTACCATCTGTAGAGAAGAGAGAAAGG ATTCGAAATCAAATCTAAGTGTCTGGGATCTCTAGACAGAGCCAGACTTTGGGCCGGGTGTCCGGCTCCT TCTGTTGGAGGTGCTCCAGGTGCCATGGAACTGGATCTGAGCCCGACTCATCTCAGCAGCTCCCCAGAAG ATGTGTGCCCAACTCCTGCTACCCCTCCTGAGACTCCTCCGCCCCCTGATAACCCTCCGCCAGGGGATGT GAAGCGGTCGCAGCCTTTGCCCATCCCCAGCAGCAGGAAACTTCGAGAAGAGGAGTTTCAGGCAACCTCT CTGCCTTCCATCCCCAACCCCTTCCCTGAGCTCTGCAGCCCACCTTCACAGAAACCCATTCTTGGTGGTT CCTCCGGTGCAAGGGGGTTGCTTCCTCGAGACTCCAGCCGCCTCTGTGTGGTGAAGGTGTACAGTGAGGA TGGGGCCTGCCGGTCTGTGGAGGTGGCAGCGGGCGCCACAGCTCGTCACGTGTGTGAGATGCTGGTACAA CGAGCTCACGCCCTGAGCGACGAGAGCTGGGGACTAGTGGAATCCCACCCCTACCTGGCACTGGAGCGGG GTCTGGAGGACCATGAATTTGTGGTGGAAGTGCAGGAGGCCTGGCCTGTGGGTGGAGACAGCCGCTTCAT CTTTCGTAAAAACTTCGCCAAGTATGAACTATTCAAGAGCCCCCCACACACCCTGTTCCCAGAAAAGATG GTCTCGAGCTGTCTGGATGCACAAACAGGCATATCCCATGAAGACCTCATCCAGAACTTCCTGAACGCTG GCAGCTTCCCTGAGATCCAGGGCTTCCTGCAGCTGCGGGGATCAGGCCGGGGGTCAGGTCGAAAGCTTTG GAAACGTTTCTTCTGCTTTCTGCGTCGATCTGGCCTCTACTACTCTACCAAGGGTACCTCCAAGGACCCC AGACACCTACAGTATGTGGCAGATGTGAATGAGTCCAATGTCTATGTGGTGACCCAGGGCCGCAAGCTGT ATGGGATGCCCACTGACTTCGGCTTCTGTGTCAAGCCCAACAAGCTTCGAAACGGCCACAAGGGGCTCCA CATCTTCTGCAGTGAGGATGAGCAGAGTCGGACCTGCTGGCTGGCTGCCTTCCGGCTCTTCAAGTACGGG GTACAGCTATATAAGAATTATCAGCAGGCCCAGTCTCGTCACCTGCGCCTATCCTATTTGGGGTCTCCAC CCTTGAGGAGCGTCTCAGACAATACCCTAGTGGCTATGGACTTCTCTGGCCATGCGGGGCGTGTCATTGA TAACCCCCGGGAAGCTCTGAGTGCCGCCATGGAGGAGGCCCAGGCCTGGAGGAAGAAGACAAACCACCGT CTGAGCCTGCCCACCACATGCTCTGGCTCGAGCCTCAGCGCAGCCATTCATCGCACCCAGCCCTGGTTTC ATGGACGCATCTCTCGGGAGGAGAGCCAGCGGCTAATTGGACAGCAGGGCCTGGTGGATGGTGTGTTCCT GGTCCGGGAGAGCCAGAGGAACCCACAGGGCTTTGTCCTGTCCTTGTGCCATCTGCAGAAAGTCAAGCAT TATCTCATTTTGCCAAGCGAAGATGAAGGTTGCCTTTACTTCAGCATGGATGAGGGCCAGACCCGTTTCA CAGACCTGCTGCAGCTGGTAGAATTCCACCAGCTGAACCGAGGCATCCTGCCCTGCCTGCTGCGCCACTG CTGTGCCCGTGTGGCCCTCTGAGGCCGCACAAGCTACTGCAGCCATGGGTTTGCCTACCACCTTTCTGTT CTGTGGACTCGGTGCAGGTGGGTGGGGTGGTAAACAGTGGAAGAGCTCCTCCCCCCCCAATTTTATCCCA TTTTTTTAAAACCTCTCTCAACCAGTGAAACATCCCCTAACCCTGTCCATCCCTGACTCCTGTCCCCAAG GGAGGCATTGTGGTCCTGTCCCCTTGGTAGAGCTCCTGAGGTACTGTTCCAGTGAGGGGCATTATGAGAG GAGCGGGGCAGCCCAGGAGGTCTCATACCCCACCCGTAATCTGTACAGACTGAGAGGCCAGTTGATCTGC TCTGTTTTATACCAGTAACAATAAAGATTATTTTTTGATAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_010346
• Insert Size: 1608 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC003295, AAH03295
• RefSeq Size: 2154 bp
• RefSeq ORF: 1608 bp
• Locus ID: 14786
• UniProt ID: Q03160
• Cytogenetics: 11 61.75 cM
• Gene Summary: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration (By similarity). Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress.[UniProtKB/Swiss-Prot Function]