P Glycoprotein (ABCB1) (NM_000927) Human 3' UTR Clone
CAT#: SC208086
3' UTR clone of ATP-binding cassette sub-family B (MDR/TAP) member 1 (ABCB1) for miRNA target validation
Product Images
Frequently bought together (2)
Other products for "P Glycoprotein"
Specifications
Product Data | |
Vector | pMirTarget |
Species | Human |
Transfection Reporter | RFP |
Assay Reporter | Luciferase |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Symbol | P Glycoprotein |
Synonyms | ABC20; CD243; CLCS; GP170; MDR1; p-170; P-GP; PGY1 |
ACCN | NM_000927 |
Insert Size | 1256 bp |
Sequence Data |
>SC208086 3’UTR clone of NM_000927
The sequence shown below is from the reference sequence of NM_000927. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGTGTCCAGGCTGGAACAAAGCGCCAGTGAACTCTGACTGTATGAGATGTTAAATACTTTTTAATATTT GTTTAGATATGACATTTATTCAAAGTTAAAAGCAAACACTTACAGAATTATGAAGAGGTATCTGTTTAA CATTTCCTCAGTCAAGTTCAGAGTCTTCAGAGACTTCGTAATTAAAGGAACAGAGTGAGAGACATCATC AAGTGGAGAGAAATCATAGTTTAAACTGCATTATAAATTTTATAACAGAATTAAAGTAGATTTTAAAAG ATAAAATGTGTAATTTTGTTTATATTTTCCCATTTGGACTGTAACTGACTGCCTTGCTAAAAGATTATA GAAGTAGCAAAAAGTATTGAAATGTTTGCATAAAGTGTCTATAATAAAACTAAACTTTCATGTGACTGG AGTCATCTTGTCCAAACTGCCTGTGAATATATCTTCTCTCAATTGGAATATTGTAGATAACTTCTGCTT TAAAAAAGTTTTCTTTAAATATACCTACTCATTTTTGTGGGAATGGTTAAGCAGTTTAAATAATTCCTG TTGTATATGTCTATTCACATTGGGTCTTACAGAACCATCTGGCTTCATTCTTCTTGGACTTGATCCTGC TGATTCTTGCATTTCCACATTAAGGTGGCTCTCAAACCCAAAACACAGATCGATATAAGATTTTAGGAG GTGGGGTGAGGCACAATTATGAAGTGCATATTATTCAGATGTATAGTAAATACTTTGCATTGCTTTTAT AAAGGGTTCTTTAAGGATTTTTTAAGATTTTTACACTTCCAAAGTACATTTACTTTTTGTCTTGATAAT GAATCACTTTTGCCAGTAATTGGCCTCTTCCAAAAGTGATCCTTCTGACTTACAGATGTTTAAAATGTG CCATGAGTTTAACTACATCTTGATACAAACATGATAAAAAAAGAAAAAAATATATTCCAAAGGTTGGGA CTCTGGACGACAAATTTTTTTAAATTAGCCAAAAAGCATTATTAACATTATAAACTATATTTACTATAA ACAATTGCTATCTTAAATAAGCAACTTCTAAAAATAAAAAAAAGAAGCCATCACCTCCAGGAAAAAAAA ATAGGAAAGGATATAATCAGGTAATTCTCAAAGAAGAAATGCATGAGAAAAATGTATACAGTTTCAACA ATCAAATAAATGCAAATTAAAACAAAATATCATTTTTTTGCCTTGTAATTTAATGATGAATAAAAAAAT CTAATGTGACATTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. |
Reference Data | |
RefSeq | NM_000927.5 |
Summary | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Feb 2017] |
Locus ID | 5243 |
MW | 49.9 |
Documents
Product Manuals |
FAQs |
SDS |
Resources
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.