SERINC5 (NM_178276) Human 3' UTR Clone

CAT#: SC206810

3' UTR clone of serine incorporator 5 (SERINC5) for miRNA target validation

Specifications

Product Data

• Vector: pMirTarget
• Species: Human
• Transfection Reporter: RFP
• Assay Reporter: Luciferase
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Symbol: SERINC5
• Synonyms: C5orf12; TPO1
• ACCN: NM_178276
• Insert Size: 537 bp
• Sequence Data:
  Insert Sequence

  >SC206810 3’UTR clone of NM_178276
  The sequence shown below is from the reference sequence of NM_178276. The complete sequence of this clone may contain minor differences, such as SNPs.
  Blue=Stop Codon Red=Cloning site
  
  GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
  TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
  GTAAGAAGTGCCTTTCACCTCCTGCCATGATTCTGAGGCCTCCCCAGCCATGTGGAACTCTGAGAAACC
  TGAACGGACTCCATTTGGCTCCTTCATTTGCAAGACATCAAGGGCTCCTTACCCACCCCCTTCCTCAAG
  GAATTAACTTGTGCAAGCTGACTCCCAGCACATCAAAGAATGCAATTAACTGATAACATGCTGTGGCAA
  GCTATGTCCGCAGTTCCCAGGAATTTGTCCAGTTGATATTACCCTAAGCCCCTGTGTTTTTGTCTGGTT
  GATAGCACCCAAAGCCCAGCGTCTATCACCTTGTGATGGATTTAAAGCCCCTGCACCTGGAACTGTTTG
  CTTTCCTGTAACCATTTGTCTTTTTAACTTCTTTTGCCTGTTTTACTTCTGTAAGACTGCTACAGCTAG
  GCTCCCCCTCCCCTCTCTAAACCAAAGTATAAAACAAAATCTAGCCCCTTCTTCAGGGCCGAGAGAATT
  TTGAGCACTAGCCGTCTCTCGGTCGCTGGCTAATAAAGGACTCCTCAATTCGTC
  ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
  CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
  
• Restriction Sites: SgfI-MluI
• OTI Disclaimer: Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

• RefSeq: NM_178276.7
• Summary: Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm (PubMed:26416733, PubMed:26416734). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes (By similarity).[UniProtKB/Swiss-Prot Function]
• Locus ID: 256987
• MW: 20.2