Desmoglein 1 (DSG1) Rabbit Polyclonal Antibody

CAT#: TA890113S

Rabbit Polyclonal anti-DSG1 Antibody

Product Images

Western blot analysis of extracts (35ug) from different cell lines and tissues by using anti-DSG1 rabbit polyclonal antibody.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:500~2000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein of human DSG1
• Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Concentration: 1.99 mg/ml
• Purification: Purified from the immunized serum by affinity chromatography (Protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 113.7 kDa
• Gene Name: desmoglein 1
• Database Link:
  NP_001933
  Entrez Gene 1828 Human
  UniProt ID Q02413
• Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
• Synonyms: CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1

Reference Data

• Protein Families: Druggable Genome