CAD Mouse Monoclonal Antibody [Clone ID: OTI10A3]
USD 200.00
Specifications
Product Data | |
Clone Name | OTI10A3 |
Applications | WB |
Recommended Dilution | WB 1:250~500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 1918-2225 of human CAD (NP_004332) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
Database Link | |
Background | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
Synonyms | CDG1Z; DEE50; EIEE50; GATD4 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Alanine, aspartate and glutamate metabolism, Metabolic pathways, Pyrimidine metabolism |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF812683 | Carrier-free (BSA/glycerol-free) CAD mouse monoclonal antibody,clone OTI10A3 |
USD 600.00 |
|
TA812683AM | CAD mouse monoclonal antibody,clone OTI10A3, Biotinylated |
USD 509.00 |
|
TA812683BM | CAD mouse monoclonal antibody,clone OTI10A3, HRP conjugated |
USD 509.00 |
|
TA812683S | CAD mouse monoclonal antibody,clone OTI10A3 |
USD 200.00 |
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