HIF-1 alpha (HIF1A) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2D5]
CAT#: TA811847AM
HIF1A mouse monoclonal antibody,clone OTI2D5, Biotinylated
Conjugation: Unconjugated HRP
USD 200.00
USD 665.00
Specifications
Product Data | |
Clone Name | OTI2D5 |
Applications | WB |
Recommended Dilution | WB 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Human recombinant protein fragment corresponding to amino acids 531-826 of human HIF1a (NP_001521) produced in E.coli. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 0.5 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Biotin |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 92.5 kDa |
Gene Name | hypoxia inducible factor 1 alpha subunit |
Database Link | |
Background | This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011] |
Synonyms | bHLHe78; HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8 |
Reference Data | |
Protein Families | Transcription Factors |
Protein Pathways | mTOR signaling pathway, Pathways in cancer, Renal cell carcinoma |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Antibody Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
CF811847 | Carrier-free (BSA/glycerol-free) HIF1A mouse monoclonal antibody,clone OTI2D5 |
USD 564.00 |
|
TA811847 | HIF1A mouse monoclonal antibody,clone OTI2D5 |
USD 447.00 |
|
TA811847BM | HIF1A mouse monoclonal antibody,clone OTI2D5, HRP conjugated |
USD 509.00 |
|
TA811847S | HIF1A mouse monoclonal antibody,clone OTI2D5 |
USD 200.00 |
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