BRIT1 (MCPH1) Mouse Monoclonal Antibody [Clone ID: OTI5F8]

CAT#: TA804882

MCPH1 mouse monoclonal antibody, clone OTI5F8 (formerly 5F8)

Product Images

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MCPH1 (RC224920, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MCPH1. Positive lysates LY411212 (100ug) and LC411212 (20ug) can be purchased separately from OriGene.

Specifications

Product Data

• Clone Name: OTI5F8
• Applications: WB
• Recommended Dilution: WB 1:500
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-264 of human MCPH1 (NP_078872) produced in E.coli.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 92.6 kDa
• Gene Name: microcephalin 1
• Database Link:
  NP_078872
  Entrez Gene 79648 Human
  UniProt ID Q8NEM0
• Background: This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]
• Synonyms: BRIT1; MCT