AMH Rabbit Monoclonal Antibody [Clone ID: OTIR1E3]
CAT#: TA592033S
AMH Rabbit monoclonal antibody, clone OTIR1E3
Size: 100 ul
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USD 200.00
Specifications
Product Data | |
Clone Name | |
Applications | ELISA |
Recommended Dilution | ELISA 1:5000-10000 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | Recombinant protein (26-560aa) of human AMH produced in HEK301 |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Predicted Protein Size | 59.17 kDa |
Gene Name | anti-Mullerian hormone |
Database Link | |
Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate N- and C-terminal cleavage products that homodimerize and associate to form a biologically active noncovalent complex. This complex binds to the anti-Mullerian hormone receptor type 2 and causes the regression of Mullerian ducts in the male embryo that would otherwise differentiate into the uterus and fallopian tubes. This protein also plays a role in Leydig cell differentiation and function and follicular development in adult females. Mutations in this gene result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2016] |
Synonyms | MIF; MIS |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
TA592033 | AMH Rabbit monoclonal antibody, clone OTIR1E3 |
USD 519.00 |
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