ERp57 (PDIA3) Rabbit Monoclonal Antibody [Clone ID: OTIR5G4]
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USD 436.00
USD 200.00
USD 867.00
Specifications
Product Data | |
Clone Name | OTIR5G4 |
Applications | SISCAPA |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PDIA3 (NP_005304). The exact sequence is proprietary. |
Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | Lot dependent; please refer to CoA along with shipment |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 56.8 kDa |
Gene Name | protein disulfide isomerase family A member 3 |
Database Link | |
Background | This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. This protein also functions as a molecular chaperone that prevents the formation of protein aggregates. [provided by RefSeq, Dec 2016] |
Synonyms | ER60; ERp57; ERp60; ERp61; GRP57; GRP58; HEL-S-93n; HEL-S-269; HsT17083; P58; PI-PLC |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Antigen processing and presentation |
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