TXNDC5 Rabbit Monoclonal Antibody [Clone ID: OTIR4D8]

CAT#: TA591035

Rabbit monoclonal anti-TXND5 antibody for SISCAPA, clone OTIR4D8

Specifications

Product Data

• Clone Name: OTIR4D8
• Applications: SISCAPA
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human TXNDC5 (NP_110437). The exact sequence is proprietary.
• Formulation: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: Lot dependent; please refer to CoA along with shipment
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 47.6 kDa
• Gene Name: thioredoxin domain containing 5
• Database Link:
  NP_110437
  Entrez Gene 105245 MouseEntrez Gene 81567 Human
  UniProt ID Q8NBS9
• Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene. [provided by RefSeq, Dec 2016]
• Synonyms: ENDOPDI; ERP46; HCC-2; HCC2; PDIA15; STRF8; UNQ364

Reference Data

• Protein Families: Druggable Genome