PBX1 Mouse Monoclonal Antibody [Clone ID: OTI1D9]

CAT#: TA502971

PBX1 mouse monoclonal antibody, clone OTI1D9 (formerly 1D9)


 Product Datasheet for 'TA502971'

  View other "OTI1D9" antibodies (2)

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USD 360.00


Availability*
In Stock

Size
    • 100 ul


Product images

Specifications

Product Data
Clone Name OTI1D9
Applications FC, IF, WB
Recommend Dilution WB 1:2000, IF 1:100, FLOW 1:100
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Full length human recombinant protein of human PBX1 (NP_002576) produced in HEK293T cell.
Isotype IgG1
Formulation PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 1 mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 46.4 kDa
Gene Name PBX homeobox 1
Background This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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