GLI3 Rabbit Polyclonal Antibody
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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications
Product Data | |
Applications | IHC |
Recommended Dilution | WB,1:500 - 1:2000 IHC,1:50 - 1:200 |
Reactivities | Mouse, Rat, Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 800-900 of human GLI3 (NP_000159.3). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 169kDa |
Gene Name | GLI family zinc finger 3 |
Database Link | |
Background | This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. |
Synonyms | ACLS; GCPS; OTTHUMP00000159085; PAP-A; PAPA; PAPA1; PAPB; PHS; PPDIV |
Reference Data |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.