Dystonin (DST) Rabbit Polyclonal Antibody

CAT#: TA375635

DST Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using DST antibody (TA375635) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit .|Exposure time: 90s.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:500 - 1:2000
  IHC,1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DST (NP_001714.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 9kDa/25kDa/50kDa/102kDa/306-860kDa
• Gene Name: dystonin
• Database Link:
  Entrez Gene 667 Human
  UniProt ID Q03001
• Background: This gene encodes a member of the plakin protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been reported that some isoforms are expressed in neural and muscle tissue, anchoring neural intermediate filaments to the actin cytoskeleton, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing intermediate filaments to hemidesmosomes. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
• Synonyms: BP240; BPA; BPAG1; CATX-15; D6S1101; DKFZp564B2416; DMH; DT; dystonin; FLJ13425; FLJ21489; FLJ30627; FLJ32235; FLJ46791; KIAA0465; KIAA0728; KIAA1470; MACF2; trabeculin-beta