THNSL1 Rabbit Polyclonal Antibody

CAT#: TA370522

THNSL1 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-2: K562 and 231 cell lysates Primary antibody: TA370522 (THNSL1 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA370522 (THNSL1 Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA370522 (THNSL1 Antibody) at dilution 1/45, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: K562 and 231 cell lysates
  IHC: 50-300
  Positive control: Human esophagus cancer
  Predicted cell location: Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human THNSL1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 83 kDa
• Gene Name: threonine synthase like 1
• Database Link:
  Entrez Gene 79896 Human
  UniProt ID Q8IYQ7
• Background: THNSL1 (threonine synthase-like 1), also known as TSH1, is a 743 amino acid member of the serine/threonine dehydratase family. Expressed primarily in brain and endocrine glands, THNSL1 is thought to function as a pyridoxal-5'-phosphate (PLP)-dependent enzyme that uses pyridoxal phosphate as a cofactor. THNSL1 shares similarity with bacterial threonine synthases (which synthesize threonine from aspartic acid), suggesting that THNSL1 may have once participated in de novo threonine synthesis within the body, but has since lost its original metabolic role.
• Synonyms: FLJ22002; TSH1