ANKRD10 Rabbit Polyclonal Antibody

CAT#: TA370333

ANKRD10 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370333 (ANKRD10 Antibody) at dilution 1/150 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA370333 (ANKRD10 Antibody) at dilution 1/150, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 200-300
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ANKRD10
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: ankyrin repeat domain 10
• Database Link:
  Entrez Gene 55608 Human
  UniProt ID Q9NXR5
• Background: ANKRD10 (Ankyrin repeat domain-containing protein 10) is a 420 amino acid protein that contains four Ankyrin repeats and is expressed as two alternatively spliced isoforms. The gene encoding ANKRD10 maps to chromosome 13. Comprising nearly 4% of the human genome, chromosome 13 contains around 114 million base pairs and encodes over 400 genes. Chromosome 13 houses key tumor suppressor genes, including BRCA2 and RB1, which are associated with breast cancer susceptibility and retinoblastoma, respectively. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
• Synonyms: DKFZp686B07190; FLJ20093