CYB5R1 Rabbit Polyclonal Antibody

CAT#: TA370044

CYB5R1 rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-3: K562 Hela and HEPG2 cell lysates Primary antibody: TA370044 (CYB5R1 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA370044 (CYB5R1 Antibody) at dilution 1/30 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA370044 (CYB5R1 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: K562，Hela and HEPG2 cell lysates
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm and Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CYB5R1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 34 kDa
• Gene Name: cytochrome b5 reductase 1
• Database Link:
  Entrez Gene 51706 Human
  UniProt ID Q9UHQ9
• Background: NADH-cytochrome b5 reductases participate in a variety of physiological processes including biosynthesis of cholesterol, methemoglobin reduction of erythrocytes, elongation of fatty acids and metabolism of drugs. CYB5R1 (cytochrome b5 reductase 1), also known as NADH-cytochrome b5 reductase 1, B5R1, NQO3A2, humb5R2 or NAD(P)H:quinone oxidoreductase type 3 polypeptide A2, is a 305 amino acid single-pass membrane protein that contains one FAD-binding FR-type domain and belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. Widely expressed, CYB5R1 binds FAD as a cofactor and is encoded by a gene located on human chromosome 1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
• Synonyms: B5R.1; B5R1; humb5R2; NQO3A2