CASK Rabbit Polyclonal Antibody

CAT#: TA369906

CASK rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Human cerebrum tissue lysate Primary antibody: TA369906 (CASK Antibody) at dilution 1/500 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA369906 (CASK Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA369906 (CASK Antibody) at dilution 1/45, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA369906 (CASK Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA369906 (CASK Antibody) at dilution 1/45, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human cerebrum tissue lysate
  IHC: 40-200
  Positive control: Human esophagus cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human CASK
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 105 kDa
• Gene Name: calcium/calmodulin dependent serine protein kinase
• Database Link:
  Entrez Gene 8573 Human
  UniProt ID O14936
• Background: This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CAGH39; CMG; FGS4; FLJ22219; FLJ31914; hCASK; LIN2; MICPCH; TNRC8