ARL17B (LOC100996709) Rabbit Polyclonal Antibody

CAT#: TA369516

ARL17A/ARL17B rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA369516 (ARL17A/ARL17B Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA369516 (ARL17A/ARL17B Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA369516 (ARL17A/ARL17B Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA369516 (ARL17A/ARL17B Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ARL17A/ARL17B
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: ADP-ribosylation factor-like protein 17
• Database Link:
  Entrez Gene 100996709 Human
  UniProt ID Q8IVW1
• Background: ARL17 (ADP-ribosylation factor-like protein 17), also known as ARF1P2 or ARL17P1, is a 177 amino acid member of the ARF protein family. In human, there are two genes which have been identified as ARL17A and ARL17B that code for identical proteins and colocalize at chromosomal position 17q21.31. ARL17 functions as an activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Localized to the Golgi apparatus, ARL17 may also be involved in the modulation of vesicle budding and uncoating within the Golgi. ARL17 is expressed as three isoforms produced by alternative splicing events.GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity).