Filamin C (FLNC) Rabbit Polyclonal Antibody

CAT#: TA368335

FLNC rabbit polyclonal antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-3: LO2 NIH/3T3 A172 cell lysates Primary antibody: TA368335 (FLNC Antibody) at dilution 1/750 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA368335 (FLNC Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA368335 (FLNC Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: LO2, NIH/3T3, A172 cell lysates
  IHC: 30-150
  Positive control: Human tonsil
  Predicted cell location: Cytoplasm and Cell membrane
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human FLNC
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 291 kDa
• Gene Name: filamin C
• Database Link:
  Entrez Gene 2318 Human
  UniProt ID Q14315
• Background: This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: ABP-280; ABP-L; ABP280A; ABPA; ABPL; Filamin-2; FLJ10186; FLN2; Gamma-filamin