UBAC2 Rabbit Polyclonal Antibody

CAT#: TA367821

UBAC2 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA367821 (UBAC2 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA367821 (UBAC2 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA367821 (UBAC2 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA367821 (UBAC2 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 20-100
  Positive control: Human ovarian cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human UBAC2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: UBA domain containing 2
• Database Link:
  Entrez Gene 337867 Human
  UniProt ID Q8NBM4
• Background: UBAC2 (ubiquitin-associated domain-containing protein 2), also known as PHGDHL1 (phosphoglycerate dehydrogenase-like protein 1), is a 344 amino acid multi-pass membrane protein that contains one UBA domain and is expressed as multiple alternatively spliced isoforms. The gene encoding UBAC2 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
• Synonyms: FLJ26351; FLJ30001; FLJ30548; FLJ42413; MGC90487; PHGDHL1; RP11-178C10.1