IL19 Rabbit Polyclonal Antibody

CAT#: TA367096

IL19 rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-2: Mouse liver tissue and Rat liver tissue lysates Primary antibody: TA367096 (IL19 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA367096 (IL19 Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using TA367096 (IL19 Antibody) at dilution 1/45, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: Mouse liver tissue and Rat liver tissue lysates
  IHC: 50-200
  Positive control: Human colorectal cancer
  Predicted cell location: Secreted
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human IL19
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 20 kDa
• Gene Name: interleukin 19
• Database Link:
  Entrez Gene 29949 Human
  UniProt ID Q9UHD0
• Background: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
• Synonyms: IL-10C; IL-19; MDA1; NG.1; ZMDA1