SSH3 Rabbit Polyclonal Antibody

CAT#: TA366497

SSH3 rabbit polyclonal antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane: 293T cell lysate Primary antibody: TA366497 (SSH3 Antibody) at dilution 1/800 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 5 minutes

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA366497 (SSH3 Antibody) at dilution 1/55 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA366497 (SSH3 Antibody) at dilution 1/55, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA366497 (SSH3 Antibody) at dilution 1/55 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human brain tissue using TA366497 (SSH3 Antibody) at dilution 1/55, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: 293T cell lysate
  IHC: 50-200
  Positive control: Human gastric cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SSH3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 73 kDa
• Gene Name: slingshot protein phosphatase 3
• Database Link:
  Entrez Gene 54961 Human
  UniProt ID Q8TE77
• Background: The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).
• Synonyms: FLJ10928; FLJ20515; FLJ42240; hSSH-3L; SSH-3L; SSH3L