Junctional Adhesion Molecule 1 (F11R) Rabbit Polyclonal Antibody

CAT#: TA366475

F11R rabbit polyclonal antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Mouse brain tissue lysate Primary antibody: TA366475 (F11R Antibody) at dilution 1/750 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 5 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse brain tissue lysate
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human F11R
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Predicted Protein Size: 33 kDa
• Gene Name: F11 receptor
• Database Link:
  Entrez Gene 50848 Human
  UniProt ID Q9Y624
• Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
• Synonyms: CD321; JAM; JAM-1; JAM-A; JAM1; JAMA; JCAM; KAT; OTTHUMP00000027880; OTTHUMP00000027881; PAM-1