ZNHIT1 Rabbit Polyclonal Antibody

CAT#: TA365182

ZNHIT1 rabbit polyclonal antibody

Product Images

Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA365182 (ZNHIT1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA365182 (ZNHIT1 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA365182 (ZNHIT1 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA365182 (ZNHIT1 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human thyroid cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Gene Name: zinc finger HIT-type containing 1
• Database Link:
  Entrez Gene 10467 Human
  UniProt ID O43257
• Background: ZNHIT1 (zinc finger, HIT-type containing 1), also known as CG1I (cyclin-G1-binding protein 1), p18 hamlet or ZNFN4A1 (zinc finger protein subfamily 4A member 1), is a 154 amino acid protein that plays a role in the induction of p53-mediated apoptosis. A member of the ZNHIT1 family, ZNHIT1 contains one HIT-type zinc finger and interacts with p38. ZNHIT1 undergoes post-translational phosphorylation and is encoded by a gene that maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
• Synonyms: CG1I; CGBP1; H_DJ0747G18.14; p18Hamlet; ZNFN4A1