Adrenomedullin (ADM) Rabbit Polyclonal Antibody

CAT#: TA363823

Rabbit anti Human Proadrenomedullin (1-20)

Specifications

Product Data

• Applications: E
• Recommended Dilution: This antibody has been tested and validated in ELISA against Proadrenomedullin (1-20).
  Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well.
  Optimal dilutions should be determined by the end user.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of Human Proadrenomedullin (1-20): H-Ala-Arg-Leu-Asp-Val-Ala-Ser-Glu-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2 coupled to carrier protein.
• Formulation: Lyophilized whole serum.
  This product contains no preservative.
• Reconstitution Method: Reconstitute with 50 ul of distilled water for the equivalent of undiluted antiserum.
• Conjugation: Unconjugated
• Storage: Store lyophilized at 2-8°C short term or at -20°C long term. After reconstitution store the antibody undiluted (in aliquots) at -20°C to -80°C. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: adrenomedullin
• Database Link:
  Entrez Gene 133 Human
  UniProt ID P35318
• Background: Proadrenomedullin, the precursor of adrenomedullin, contains a unique 20-residue sequence termed proadrenomedullin NH₂ terminal 20 peptide (PAMP). It has been suggested that PAMP functions as an inhibitory modulator of renal noradrenergic neurotransmission and plays an important role in regulating renal functions. Also, PAMP can act as an inhibitory regulator of adrenal catecholamine release in vivo and has a potent hyperglycemic effect after intra-third cerebroventricular administration in fasted mice.
• Synonyms: adrenomedullin; AM; preproadrenomedullin