PLOD1 Rabbit Polyclonal Antibody

CAT#: TA362064

PLOD1 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: PLOD1 Sample Tissue: Human 786-0 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PLOD1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 79 kDa
• Gene Name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
• Database Link:
  NP_000293.2
  Entrez Gene 5351 Human
  UniProt ID Q02809
• Background: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: FLJ42041; LH; LH1; LLH; PLOD

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Lysine degradation