Syt1 Rabbit Polyclonal Antibody

CAT#: TA357593

Syt1 Antibody - middle region

Product Images

Syt1 antibody - middle region (TA357593) validated by WB using Mouse Spleen lysate at 1.0ug/ml.

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  Lanes: Lane1: 10ug mouse cortex brain lysate Lane2: 25ug mouse cortex brain lysate Lane3: 40ug mouse cortex brain lysate Primary Antibody Dilution: 1:1000 Secondary Antibody: Anti-rabbit HRP Secondary Antibody Dilution: 1:2000 Gene Name: Syt1 Submitted by: Anonymous

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  Sample Type: complete mouse retina sections Red: Primary Blue: DAPI Primary Dilution: 1:200 Secondary Antibody: Goat anti-Rabbit AF568 IgG(H+L) Secondary Dilution: 1:200 Image Submitted by: David Zenisek Yale UniversityÂ

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  Sample Type:Â outer mouse plexiform layer Red:Â Primary Blue:Â DAPI Primary Dilution:Â 1:200 Secondary Antibody:Â Goat anti-Rabbit AF568 IgG(H+L) Secondary Dilution:Â 1:200 Image Submitted by:Â David Zenisek Yale UniversityÂ

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 47kDa
• Gene Name: synaptotagmin I
• Database Link:
  NP_033332
  Entrez Gene 20979 Mouse
  UniProt ID P46096
• Background: Syt1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2.
• Synonyms: DKFZp781D2042; P65; SVP65; SYT; SytI