Acid sphingomyelinase (SMPD1) Rabbit Polyclonal Antibody

CAT#: TA355781

SMPD1 Antibody - middle region

Product Images

Host: Rabbit Target Name: SMPD1 Sample Tissue: Human THP-1 Whole Cell Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SMPD1
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
  Homology: Cow: 83%; Dog: 87%; Guinea Pig: 87%; Horse: 80%; Human: 100%; Mouse: 80%; Rabbit: 87%; Rat: 87%; Sheep: 83%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 18kDa
• Gene Name: sphingomyelin phosphodiesterase 1
• Database Link:
  NP_000534.3
  Entrez Gene 6609 Human
  UniProt ID P17405
• Background: The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
• Synonyms: ASM; aSMase; NPD

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Lysosome, Metabolic pathways, Sphingolipid metabolism