TRPV4 Rabbit Polyclonal Antibody

CAT#: TA355762

TRPV4 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: TRPV4 Sample Type: HT1080 Whole cell lysates Antibody Dilution: 1.0ug/ml

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  WB Suggested Anti-TRPV4 antibody Titration: 1 ug/mL Sample Type: Human heart

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  Rabbit Anti-TRPV4 Antibody Catalog Number: TA355762 Formalin Fixed Paraffin Embedded Tissue: Human Adult heart Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5–2.0 sec Protocol located in Reviews and Data.

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human TRPV4
• Specificity: Expected reactivity: Cow, Dog, Human, Mouse, Pig, Rat
  Homology: Cow: 85%; Dog: 92%; Human: 100%; Mouse: 86%; Pig: 92%; Rat: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 60kDa
• Gene Name: transient receptor potential cation channel subfamily V member 4
• Database Link:
  NP_001170899.1
  Entrez Gene 59341 Human
  UniProt ID Q9HBA0
• Background: This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: OTRPC4; TRP12; VR-OAC; VRL-2; VRL2; VROAC

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane