Utrophin (UTRN) Mouse Monoclonal Antibody [Clone ID: DRP3/20C5]

CAT#: TA355356

Utrophin Mouse Monoclonal Antibody

Specifications

Product Data

• Clone Name: DRP3/20C5
• Applications: IHC
• Recommended Dilution: 1:2 - 1:10
• Reactivities: Human, Dog, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Fusion protein containing the first 261 amino acids of the published DMDL gene sequence
• Specificity: Amino terminal domain of the human homolog of human dystrophin, utrophin (also known as dystrophin related protein or "DRP”). Also crossreacts with utrophin in sections of muscle from rat and dog. Other animals species have not been tested.
• Formulation: Lyophilized tissue culture supernatant containing sodium azide as a preservative.
• Reconstitution Method: The user is required to reconstitute the contents of the vial with the correct volume of sterile distilled water as indicated on the vial label
• Conjugation: Unconjugated
• Storage: Store at 2-8°C
• Stability: 12 months
• Gene Name: utrophin
• Database Link:
  Entrez Gene 7402 Human
  UniProt ID P46939
• Background: The utrophin gene is located on chromosome 6. The protein is a homologue of dystrophin and is known as dystrophin-related protein. In normal muscle, utrophin is restricted to neuromuscular junctions; however, in dystrophin-deficient muscle, utrophin expression may be upregulated and labeling appears around the periphery of most fibers. lmmunohistochemical staining with DRP2 labels vessels and neuromuscular junctions and the upregulated form of utrophin, located around fiber membranes.
• Synonyms: DMDL; DRP; DRP1; FLJ23678; utrophin