TMEM49 (VMP1) Rabbit Polyclonal Antibody

CAT#: TA351822

Rabbit Polyclonal Anti-VMP1 Antibody

Product Images

Gel: 8%SDS-PAGE Lysate: 40 μg Lane 1-4: Human plasma solution HepG2 cell 293T cell Hela cell lysates Primary antibody: TA351822 (VMP1 Antibody) at dilution 1/800 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351822 (VMP1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351822 (VMP1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA351822 (VMP1 Antibody) at dilution 1/50 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA351822 (VMP1 Antibody) at dilution 1/50, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Human plasma solution, HepG2 cell, 293T cell, Hela cell lysates
  IHC: 50-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm and Nucleus
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human VMP1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: vacuole membrane protein 1
• Database Link:
  NP_112200
  Entrez Gene 81671 Human
  UniProt ID Q96GC9
• Background: VMP1 (Vacuole membrane protein 1), is a 406 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum-golgi intermediate compartment membrane. Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion.
• Synonyms: EPG3; TANGO5; TMEM49

Reference Data

• Protein Families: Transmembrane