Talin 1 (TLN1) Rabbit Polyclonal Antibody

CAT#: TA351785

Rabbit Polyclonal Anti-TLN1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Huvec cells Primary antibody: TA351785 (TLN1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 5 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351785 (TLN1 Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351785 (TLN1 Antibody) at dilution 1/35, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351785 (TLN1 Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351785 (TLN1 Antibody) at dilution 1/35, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Huvec cells
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm and Cell membrane
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human TLN1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 270 kDa
• Gene Name: talin 1
• Database Link:
  NP_006280
  Entrez Gene 21894 MouseEntrez Gene 7094 Human
  UniProt ID Q9Y490
• Background: This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells.
• Synonyms: ILWEQ; TLN

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Focal adhesion