JM4 (PRAF2) Rabbit Polyclonal Antibody

CAT#: TA351614

Rabbit Polyclonal Anti-PRAF2 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-4: Human fetal brain tissue A549 cells hela cells 293T cells Primary antibody: TA351614 (PRAF2 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351614 (PRAF2 Antibody) at dilution 1/35 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA351614 (PRAF2 Antibody) at dilution 1/35, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human fetal brain tissue and A549 cells, hela and 293T cells
  IHC: 25-100
  Positive control: Human breast cancer
  Predicted cell location: Cytoplasm or Cell membrane
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PRAF2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 19 kDa
• Gene Name: PRA1 domain family member 2
• Database Link:
  NP_009144
  Entrez Gene 54637 MouseEntrez Gene 11230 Human
  UniProt ID O60831
• Background: JM4 (Jena-Muenchen 4), also known as PRAF2 (PRA1 domain family, member 2), is a 178 amino acid endosomal multi-pass membrane protein involved in vesicular trafficking and Endoplasmic reticulum/Golgi transport. As a member of the PRA1 family, JM4 contains four putative transmembrane (TM) domains, interacts with the CC chemokine receptor 5 (CCR5) and colocalizes with Calnexin in the ER and mannose 6-phosphate receptor (CD-MPR) in the Golgi apparatus.
• Synonyms: JM4; Yip6a

Reference Data

• Protein Families: Transmembrane