PNPT1 Rabbit Polyclonal Antibody

CAT#: TA351546

Rabbit Polyclonal Anti-PNPT1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-5: Jurkat cells Hela cells A431 cells mouse liver tissue tissue 293T cells Primary antibody: TA351546 (PNPT1 Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA351546 (PNPT1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA351546 (PNPT1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351546 (PNPT1 Antibody) at dilution 1/40 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA351546 (PNPT1 Antibody) at dilution 1/40, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Jurkat, Hela and A431 cells, mouse liver tissue and 293T cells
  IHC: 50-200
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human PNPT1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 86 kDa
• Gene Name: polyribonucleotide nucleotidyltransferase 1
• Database Link:
  NP_149100
  Entrez Gene 71701 MouseEntrez Gene 87178 Human
  UniProt ID Q8TCS8
• Background: The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7.
• Synonyms: COXPD13; DFNB70; old-35; OLD35; PNPASE

Reference Data

• Protein Pathways: Purine metabolism, Pyrimidine metabolism, RNA degradation