Jagged 2 (JAG2) Rabbit Polyclonal Antibody

CAT#: TA351308

Rabbit Polyclonal Anti-JAG2 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA351308 (JAG2 Antibody) at dilution 1/30 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA351308 (JAG2 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351308 (JAG2 Antibody) at dilution 1/30 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351308 (JAG2 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 50-200
  Positive control: Human colon cancer
  Predicted cell location: Cytoplasm or Nucleus
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human JAG2
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: jagged 2
• Database Link:
  NP_660142
  Entrez Gene 3714 Human
  UniProt ID Q9Y219
• Background: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
• Synonyms: HJ2; SER2

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Notch signaling pathway