Desmoglein 1 (DSG1) Rabbit Polyclonal Antibody

CAT#: TA351136

Rabbit Polyclonal Anti-DSG1 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Human tongue cancer tissue Primary antibody: TA351136 (DSG1 Antibody) at dilution 1/750 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2 minutes

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Human tongue cancer tissue
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human DSG1
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 114 kDa
• Gene Name: desmoglein 1
• Database Link:
  NP_001933
  Entrez Gene 1828 Human
  UniProt ID Q02413
• Background: Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
• Synonyms: CDHF4; DG1; DSG; EPKHE; EPKHIA; PPKS1; SPPK1

Reference Data

• Protein Families: Druggable Genome