Cell adhesion molecule 4 (CADM4) Rabbit Polyclonal Antibody

CAT#: TA351025

Rabbit Polyclonal Anti-CADM4 Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane 1-2: RAW264.7 cells mouse brain tissue Primary antibody: TA351025 (CADM4 Antibody) at dilution 1/300 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 20 seconds

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351025 (CADM4 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TA351025 (CADM4 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA351025 (CADM4 Antibody) at dilution 1/25 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using TA351025 (CADM4 Antibody) at dilution 1/25, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: RAW264.7 cells and mouse brain tissue
  IHC: 25-100
  Positive control: Human liver cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CADM4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 43 kDa
• Gene Name: cell adhesion molecule 4
• Database Link:
  NP_660339
  Entrez Gene 260299 MouseEntrez Gene 365216 RatEntrez Gene 199731 Human
  UniProt ID Q8NFZ8
• Background: IGSF4C (immunoglobulin superfamily member 4C), also known as CADM4 (cell adhesion molecule 4), NECL4 or TSLL2, is a 388 amino acid single-pass type I membrane protein that contains one Ig-like V-type domain and two Ig-like C2-type domains. Expressed in kidney, brain and prostate, IGSF4C exists as both a monomer and a homodimer and is thought to be involved in cell-cell adhesion, possibly playing a role in tumor suppression. Human IGSF4C shares 98% sequence identity with its mouse counterpart, suggesting a conserved role between species. The gene encoding IGSF4C maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs)
• Synonyms: IGSF4C; Necl-4; NECL4; synCAM4; TSLL2

Reference Data

• Protein Families: Transmembrane