NEK10 Rabbit Polyclonal Antibody

CAT#: TA350923

Rabbit Polyclonal Anti-NEK10 Antibody

Product Images

Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA350923 (NEK10 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA350923 (NEK10 Antibody) at dilution 1/20, treated with synthetic peptide. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC: 25-100
  Positive control: Human gasrtic cancer
  Predicted cell location: Luminal membranous
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human NEK10
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: NIMA related kinase 10
• Database Link:
  NP_689747
  Entrez Gene 152110 Human
  UniProt ID Q6ZWH5
• Background: Nek10 (NIMA (never in mitosis gene a)-related kinase 10) is a 712 amino acid protein belonging to the NIMA subfamily of kinases and functions as a magnesium-dependent serine/threonine protein kinase. Kinases of the NIMA subfamily are typically involved in genotoxic stress response and DNA replication. Nek10 is expressed in brain and may contain a 14-3-3 interaction motif in its C-terminus. The gene encoding Nek10 has been localized to a region on chromosome 3 that may contribute to vulnerability to addictions. Due to alternative splicing events, three isoforms exist for Nek10.
• Synonyms: FLJ32685

Reference Data

• Protein Families: Druggable Genome, Protein Kinase