Gastric Inhibitory Polypeptide Receptor (GIPR) Rabbit Polyclonal Antibody

CAT#: TA350912

Rabbit Polyclonal Anti-GIPR Antibody

Product Images

Gel: 10%SDS-PAGE Lysate: 40 μg Lane: Mouse pancreas tissue Primary antibody: TA350912 (GIPR Antibody) at dilution 1/200 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse pancreas tissue
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human GIPR
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 53 kDa
• Gene Name: gastric inhibitory polypeptide receptor
• Database Link:
  NP_000155
  Entrez Gene 381853 MouseEntrez Gene 2696 Human
  UniProt ID P48546
• Background: This gene encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
• Synonyms: PGQTL2

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction