CEACAM3 Rabbit Polyclonal Antibody

CAT#: TA350818

Rabbit Polyclonal Anti-CEACAM3 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane: Mouse lung tissue Primary antibody: TA350818 (CEACAM3 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA350818 (CEACAM3 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using TA350818 (CEACAM3 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA350818 (CEACAM3 Antibody) at dilution 1/30 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA350818 (CEACAM3 Antibody) at dilution 1/30, treated with synthetic peptide. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Mouse lung tissue
  IHC: 25-100
  Positive control: Human gastric cancer
  Predicted cell location: cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human CEACAM3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: carcinoembryonic antigen related cell adhesion molecule 3
• Database Link:
  NP_001806
  Entrez Gene 384557 MouseEntrez Gene 1084 Human
  UniProt ID P40198
• Background: This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described.
• Synonyms: CD66D; CEA; CGM1; W264; W282

Reference Data

• Protein Families: Transmembrane