Transglutaminase 4 (TGM4) Rabbit Polyclonal Antibody

CAT#: TA350532

Rabbit Polyclonal Anti-TGM4 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane 1-5: Hela lncap skov3 293T and TM4 cell Primary antibody: TA350532 (TGM4 Antibody) at dilution 1/400 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA350532 (TGM4 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA350532 (TGM4 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA350532 (TGM4 Antibody) at dilution 1/20 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using TA350532 (TGM4 Antibody) at dilution 1/20, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela, lncap, skov3, 293T and TM4 cell
  IHC: 25-100
  Positive control: Human prostate cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human TGM4
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 77 kDa
• Gene Name: transglutaminase 4
• Database Link:
  NP_003232
  Entrez Gene 7047 Human
  UniProt ID P49221
• Background: Transglutaminase 4 also known as TGM4, TGP or hTGP, is a typical TGase that is specifically expressed in prostate tissue. TGM4 are intercellularly localizing, Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. TGases influence numerous biological processes including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis.
• Synonyms: hTGP; TGP

Reference Data

• Protein Families: Druggable Genome