RPA34 (RPA2) Rabbit Polyclonal Antibody

CAT#: TA350368

Rabbit Polyclonal Anti-RPA2 Antibody

Product Images

Gel: 12%SDS-PAGE Lysate: 40 μg Lane 1-7: Hela cells HUVEC cells HepG2 cells A549 cells Jurkat cells 231 cells A431 cells Primary antibody: TA350368 (RPA2 Antibody) at dilution 1/650 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 10 seconds

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA350368 (RPA2 Antibody) at dilution 1/45 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human breast cancer tissue using TA350368 (RPA2 Antibody) at dilution 1/45, treated with fusion protein. (Original magnification: ×200)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 500-2000
  WB positive control: Hela, huvec, HepG2, A549, Jurkat, 231 and A431 cells
  IHC: 30-150
  Positive control: Human breast cancer
  Predicted cell location: Nucleus and Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Full length fusion protein
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: replication protein A2
• Database Link:
  NP_002937
  Entrez Gene 6118 Human
  UniProt ID P15927
• Background: Replication protein A 32 kDa subunit is a protein that in humans is encoded by theRPA2 gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
• Synonyms: REPA2; RP-A p32; RP-A p34; RPA32

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: DNA replication, Homologous recombination, Mismatch repair, Nucleotide excision repair