SIGLEC5 Rabbit Polyclonal Antibody

CAT#: TA349764

Rabbit Polyclonal Anti-SIGLEC5 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: Mouse liver tissue Primary antibody: TA349764 (SIGLEC5 Antibody) at dilution 1/350 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 2minutes

• 

  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349764 (SIGLEC5 Antibody) at dilution 1/30 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using TA349764 (SIGLEC5 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349764 (SIGLEC5 Antibody) at dilution 1/30 (Original magnification: ×200)

• 

  Immunohistochemistry of paraffin-embedded Human colon cancer tissue using TA349764 (SIGLEC5 Antibody) at dilution 1/30, treated with fusion protein. (Original magnification: ×200)

Show all 5 images

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 200-1000
  WB positive control: Mouse liver tissue
  IHC: 50-200
  Positive control: Human gasrtic cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human SIGLEC5
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 61 kDa
• Gene Name: sialic acid binding Ig like lectin 5
• Database Link:
  NP_003821
  Entrez Gene 8778 Human
  UniProt ID O15389
• Background: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion
• Synonyms: CD33L2; CD170; OB-BP2; OBBP2; SIGLEC-5

Reference Data

• Protein Families: Druggable Genome, Transmembrane