Alkaline Phosphatase (ALPP) Rabbit Polyclonal Antibody

CAT#: TA349679

Rabbit Polyclonal Anti-ALPP Antibody

Product Images

Gel: 15%SDS-PAGE Lysate: 40 μg Lane 1-2: HepG2 cells human placenta tissue Primary antibody: TA349679 (ALPP Antibody) at dilution 1/1550 Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution Exposure time: 1 second

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349679 (ALPP Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human lung cancer tissue using TA349679 (ALPP Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349679 (ALPP Antibody) at dilution 1/60 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TA349679 (ALPP Antibody) at dilution 1/60, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: HepG2 cells and human placenta tissue
  IHC: 50-200
  Positive control: Human lung cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ALPP
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 58 kDa
• Gene Name: alkaline phosphatase, placental
• Database Link:
  NP_001623
  Entrez Gene 250 Human
  UniProt ID P05187
• Background: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
• Synonyms: ALP; PALP; PLAP; PLAP-1

Reference Data

• Protein Pathways: Folate biosynthesis, Metabolic pathways