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Nucleoside Diphosphate Kinase 7 (NME7) Rabbit Polyclonal Antibody
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USD 436.00
USD 200.00
USD 867.00
Specifications
| Product Data | |
| Applications | WB |
| Recommended Dilution | WB: 200-1000 WB positive control: 293T cells |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human NME7 |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 42 kDa |
| Gene Name | NME/NM23 family member 7 |
| Database Link | |
| Background | nm23-H7, also known as NME7 (non-metastatic cells 7), is a 376 amino acid protein that contains one DM10 domain and belongs to the NDK family. Using magnesium as a cofactor, nm23-H7 functions to catalyze the ATP-dependent creation of nucleoside triphosphates, thereby playing an essential role in metabolic pathways throughout the body. The gene encoding nm23-H7 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson?s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Synonyms | CFAP67; MN23H7; NDK 7; NDK7; nm23-H7 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
Documents
| Product Manuals |
| FAQs |
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