CD61 (ITGB3) Rabbit Polyclonal Antibody

CAT#: TA349357

Rabbit Polyclonal Anti-ITGB3 Antibody

Product Images

Gel: 6%SDS-PAGE Lysate: 40 μg Lane: HUVEC cell lysate Primary antibody: TA349357 (ITGB3 Antibody) at dilution 1/1000 Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution Exposure time: 1 minute

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA349357 (ITGB3 Antibody) at dilution 1/150 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TA349357 (ITGB3 Antibody) at dilution 1/150, treated with fusion protein. (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349357 (ITGB3 Antibody) at dilution 1/150 (Original magnification: ×200)

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  Immunohistochemistry of paraffin-embedded Human tonsil tissue using TA349357 (ITGB3 Antibody) at dilution 1/150, treated with fusion protein. (Original magnification: ×200)

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Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1000-5000
  WB positive control: HUVEC cell lysate
  IHC: 150-300
  Positive control: Human prostate cancer
  Predicted cell location: Cytoplasm
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human ITGB3
• Formulation: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 87 kDa
• Gene Name: integrin subunit beta 3
• Database Link:
  NP_000203
  Entrez Gene 16416 MouseEntrez Gene 29302 RatEntrez Gene 3690 Human
  UniProt ID P05106
• Background: The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
• Synonyms: BDPLT2; BDPLT16; CD61; GP3A; GPIIIa; GT

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Regulation of actin cytoskeleton